Traditional dermal fillers, like those made from hyaluronic acid (HA), provide instant volume by physically filling in wrinkles or hollow areas. They are ideal for immediate results but typically require maintenance as the filler is eventually absorbed by the body. Bio-stimulators like Sculptra, Radiesse and Profhilo work differently. They don't just fill in areas—they stimulate your body’s natural collagen production, leading to gradual, long-lasting improvements in skin texture, elasticity, and volume.
✔ Sculptra is best for those looking for a subtle, gradual improvement in facial volume and skin quality.
✔ Radiesse provides both immediate lift and long-term collagen stimulation, making it suitable for areas requiring more structural support.
✔ Profhilo focuses on hydrating and bio remodelling the skin, making it perfect for those looking to improve overall skin quality and firmness without adding significant volume.

The longevity of results varies depending on the bio-stimulator used:
✔ Sculptra: Results develop gradually over a few months as collagen production increases. The effects can last up to 2 years or more, with maintenance sessions typically recommended to prolong the results.
✔ Radiesse: Provides immediate results with the added benefit of collagen stimulation. The results can last up to 12-18 months, depending on the treatment area and individual factors.
✔ Profhilo: Usually requires two initial treatments spaced a month apart, followed by a third treatment spaced 4 months apart. Results can last up to 6-9 months, with follow-up treatments recommended to maintain skin hydration and firmness.

Bio-stimulators are versatile and can be used to treat various areas of the face and body:
✔ Sculptra is commonly used for facial volumisation, including areas like the temples, cheeks, nasolabial folds and jawline. It's also used off-label for body treatments, such as the buttocks (often referred to as a "non-surgical butt lift") and to improve skin laxity on the thighs and arms.
✔ Radiesse is typically used for deeper wrinkles and folds, such as the nasolabial folds, marionette lines and pre-jowl area. It's also TGA-approved for hand rejuvenation, providing volume and improving skin quality.
✔ Profhilo is most often used to treat skin laxity in the face, neck, and décolletage, but it can also be applied to other areas with crepey skin, such as the arms, hands and abdomen.

As with any cosmetic treatment, there are potential side effects and risks associated with bio-stimulators, though they are generally well-tolerated:
✔ Sculptra: Common side effects include injection site swelling, redness, bruising and tenderness. Rarely, small lumps or nodules may develop under the skin, which are typically not visible and can be managed with massage or additional treatments.
✔ Radiesse: Side effects may include bruising, swelling and redness at the injection site. In rare cases, there may be lumps or nodules that can be felt under the skin. As with any injectable, there is a risk of vascular occlusion if not injected properly.
✔ Profhilo: This treatment has a low risk of side effects, with mild swelling or bruising at the injection site being the most common. Since Profhilo is not a volumising filler but rather a skin enhancer, the risks of lumps or nodules are minimal.